Diablo 4’s second season, the Season of Blood, has been in full swing since its release in early October. With new content for the season teased during the recently concluded BlizzCon 2023, now is a good time to optimize your gear by defeating the new endgame bosses introduced in the update. Their Unique and Uber Unique drops will make your hero the scourge of evil.

Players have five Uber Bosses to choose from for target-farming these extremely rare items, each with their own conditions for summoning. There’s no harm in starting small and no rush to get the best items in the game. So, whether doing the grind yourself or getting a helping hand from KBoosting or other services, this guide is for you.

As a general rule, before each Uber Boss fight, max out a specific elemental resistance as much as possible. Otherwise, you’ll be in a world of hurt.

Grigoire, the Galvanic Saint

On World Tiers III and IV, the Hall of the Penitent is home to Grigoire, the Galvanic Saint. His signature skill is the lightning grid, infusing random squares of the field with lightning attacks. Its downside is that he stays still while doing so, leaving him vulnerable if you manage to get close enough. His other attacks are easy to dodge if you stay behind him as much as possible.

Summoning Grigoire requires five pieces of Living Steel in World Tier IV (two in World Tier III). Most Living Steel can be found in the Tortured Offering in Helltide.

Grigoire’s rewards

Grigoire drops Penitent Greaves for all classes. For class-specific drops:

  • Barbarian: Ancient’s Oath, Battle Trance, the Butcher’s Cleaver, Rage of Harrogath, Ramaladni’s Magnum Opus
  • Druid: The Butcher’s Cleaver, Hunter’s Zenith, Insatiable Fury, Waxing Gibbous
  • Necromancer: Blood Artisan’s Cuirass, Greaves of the Empty Tomb, Howl from Below
  • Rogue: Grasp of Shadow, Windforce, Word of Hakan
  • Sorcerer: Gloves of the Illuminator, Iceheart Brais, Staff of Lam Esen

There’s also a chance to drop Demonbinder Mount Armor, a cosmetic for your trusty steed.

Echo of Varshan

The Echo of Varshan lies in the Malignant Burrow and can be fought on World Tiers III and IV. It’s one of, if not, the hardest of the Uber Bosses because of its destructive shadow AoE attacks, which can kill players in one hit. As such, gamers advise taking on the boss with other players to force it to divide its attention. Crowd control attacks are highly effective in staggering it.

Summoning Varshan is also a chore, requiring all three Malignant Body Parts for World Tier III (for World Tier IV, it also requires a Malignant Heart). The Tree of Whispers is the best source, as it guarantees a body part. Alternatively, the alchemist can convert excess parts to needed ones.

Varshan’s drops

The most notable of Varshan’s drops are the Malignant Rings. Each class has its own ring.

  • Barbarian: Ring of Red Furor
  • Druid: Airidah’s Inexorable Will
  • Necromancer: Ring of the Sacrilegious Soul
  • Rogue: Writhing Band of Trickery
  • Sorcerer: Tal Rasha’s Iridescent Loop

Adding to the rings are three other Uniques, also corresponding to a class.

  • Barbarian: 100,000 Steps, Field of Crimson, Gohr’s Devastating Grips
  • Druid: Greatstaff of the Crone, Mad Wolf’s Glee, Vasily’s Prayer
  • Necromancer: Bloodless Scream, Deathless Visage, Deathspeaker’s Pendant
  • Rogue: Condemnation, Eyes in the Dark, Skyhunter
  • Sorcerer: Esu’s Heirloom, Raiment of the Infinite, Staff of Endless Rage

Varshan also drops Frostburn and Mother’s Embrace, Uniques that can be used by any class. It also has a chance to reward the Flesh-Weld Rod Trophy as a mount cosmetic.

The Beast in the Ice

Don’t let its rather generic name lull you into false confidence. Located at the Glacial Fissure, the Beast in the Ice is treated as a Nightmare Dungeon, a gameplay mode that buffs dungeon enemies and limits a player’s number of revives. If you exhaust the revives provided by your Nightmare Sigils, you’ll need to farm a fresh batch to challenge the boss again.

The recipe for one Nightmare Sigil calls for nine units of Distilled Fear and 250 units of Sigil Powder. Distilled Fear can only be farmed in Tier 30+ Nightmare Dungeons, which don’t always drop them. The Sigil can only be crafted by an occultist.

Without enough Cold resistance, the Beast’s series of Cold-attribute attacks can inflict Chill and Freeze, slowing or stopping your movement. It’s also a fight you don’t want to do in multiplayer, as the Beast’s Chill and Freeze stacks with the number of challengers in the arena. You can avoid most of its attacks by getting on the boss’s rear as much as possible.

Beast’s loot

This boss drops a lot of Uniques and Uber Uniques. Non-class-specific drops include Fists of Fate, Frostburn, Mother’s Embrace, and Tassets of the Dawning Sky. For class-specific ones:

  • Barbarian: 100,000 Steps, Ancient’s Oath, Battle Trance, Fields of Crimson, Hellhammer
  • Druid: Hunter’s Zenith, Insatiable Fury, Storm’s Companion, Waxing Gibbous
  • Necromancer: Bloodless Scream, Deathspeaker’s Pendant, Howl from Below, Ring of Mendeln
  • Rogue: Condemnation, Eaglehorn, Windforce, Word of Hakan
  • Sorcerer: Esu’s Heirloom, Gloves of the Illuminator, the Oculus, Staff of Lam Esen

As for mount cosmetics, the Beast can drop the Skull Torch and Fell Steed trophies.

Lord Zir, the Dark Master

Lord Zir is one of two Uber Bosses that can only be found in World Tier IV (the other being Duriel, but more on that later). Unlike the Beast in the Ice, however, summoning Lord Zir only requires nine units of Exquisite Blood, dropped by World Tier IV world bosses. His domain is located in the Ancient’s Seat.

Although he uses Fire-based attacks, Lord Zir can inflict Slow and Poison on you with his Blood Pools ability. He’ll also let loose his Blood Seekers that can inflict crowd control effects or even a one-hit kill. To counter this, it’s advisable to force Zir and his minions into a corner and inflict AoE damage on them. Some of his attacks will also give you advance notice.

Lord Zir’s rewards

Lord Zir drops Penitent Greaves, Razorplate, and Temerity, usable by all classes. The class-specific drops are as follows:

  • Barbarian: The Butcher’s Cleaver, Gohr’s Devastating Grips, Overkill, Rage of Harrogath, Ramaladni’s Magnum Opus
  • Druid: The Butcher’s Cleaver, Fleshrender, Greatstaff of the Crone, Mad Wolf’s Glee, Vasily’s Prayer
  • Necromancer: Blood Artisan’s Cuirass, Deathless Visage, Greaves of the Empty Tomb, Lidless Wall
  • Rogue: Asheara’s Khanjar, Eyes in the Dark, Grasp of Shadow, Skyhunter
  • Sorcerer: Esadora’s Overflowing Cameo, Iceheart Brais, Raiment of the Infinite, Staff of Endless Rage

He’s also the only boss who drops the Diadem of the Ancient Helm. While purely cosmetic, wearing it can make your character appear powerful.

Echo of Duriel

Long-time Diablo players recognize the King of Maggots from the second game, so his addition to Diablo IV as an Uber Boss is nothing short of exciting. His summoning requirements are also unique, if not difficult, as these involve defeating Varshan for its Mucus-Slick Egg and Grigoire for his Shard of Agony. You need two of each to summon Duriel.

At Level 100, Duriel is the toughest of the Season of Blood Uber Bosses. Expect this monstrosity to throw its unending numbers of maggots and insects at you—and that’s on top of its poisonous attacks from the front and underground. Duriel is so hard the boss fight is designed to be retriable without consuming the summoning materials, as long as you don’t reset the dungeon.

Duriel’s drops

Amid the difficulty, Duriel’s drops are arguably the best among the new endgame bosses. It has a greater chance of dropping Uber Uniques out of the five.

  • Doombringer (Barbarian, Necromancer, Rogue)
  • The Grandfather (Barbarian, Necromancer)
  • Ahavarion Spear of Lycander (Druid, Sorcerer)
  • Melted Heart of Selig
  • Andariel’s Visage
  • Harlequin Crest
  • Ring of Starless Skies

Its collection of Uniques is nothing to scoff at, either.

  • Barbarian: Azurewrath, Tuskhelm of Joritz the Mighty
  • Druid: Dolmen Stone, Tempest Roar
  • Necromancer: Black River, Blood Moon Breeches
  • Rogue: Cowl of the Nameless, Scoundrel’s Leathers
  • Sorcerer: Blue Rose, Flamescar
  • All classes: Banished Lord’s Talisman, Flickerstep, Godslayer’s Crown, Soulbrand, Tibault’s Will, X’Fal’s Corroded Signet

Duriel also drops the Smouldering Brimstone skin for your mount.


With the game’s randomized loot drops, it’s hard not to feel excited about what you’ll get with every boss felled. But it’s a different case for Uber Bosses. They may be more of a pain to kill than your average boss, but the loot they leave behind is worth the fight.

Unless it’s Uber Lilith, don’t bother with her anymore after fighting her once.

About the author

Kyrie Mattos